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Depression and Long-Term Conditions
Key Information
- The Connection: Living with a long-term condition (such as diabetes, heart disease, or chronic pain) can be both physically and emotionally demanding. The daily burden of symptoms, medications, and appointments can naturally lead to low mood or depression.
- The Vicious Cycle: The relationship works both ways. Untreated depression drains your energy and motivation, making it much harder to manage your physical health (for example taking medication, attending appointments, or maintaining healthy habits).
- Physical Impact of Depression: Depression is not just “in your head.” It can increase stress hormones and inflammation, and can make you more sensitive to pain.
- Breaking the Cycle: The key is to treat both your mental and physical health together. Treating depression helps restore energy and motivation, while better physical health can improve your mood.
What Happens Next?
Please do not see low mood as a weakness or something separate from your physical health. It is an important part of your overall wellbeing.
If you are living with a long-term condition and struggling with your mood, please let us know so we can support you with both aspects of your health.
Further Information
For advice on how to look after your mental wellbeing while living with a physical illness, please visit the NHS website.
Last reviewed: 22 March 2026
Next review due: 22 March 2029